New funding puts Viral Vector Manufacturing Facility in winning position

Children’s Medical Research Institute warmly welcomes the NSW Government’s announcement of its allocation in the 2022/23 Budget of $101.4m toward a commercial-scale Viral Vector Manufacturing Facility. This significant investment will greatly advance the ability to treat children with serious genetic diseases. In addition to funds to build the manufacturing facility, the $101.4 million commitment includesContinue reading “New funding puts Viral Vector Manufacturing Facility in winning position”

Partnership for RNA Project

Scientists from Children’s Medical Research Institute (CMRI) have partnered with RNA researchers from the Monash Institute of Pharmaceutical Sciences (MIPS) to combine mRNA delivery with viral gene delivery to treat metabolic liver disease in infants and children. The partnership will be funded by a $99k grant from the mRNA Victoria Research Acceleration Fund along with grantsContinue reading “Partnership for RNA Project”

Research Collaboration Announced Between CMRI and DiNAQOR to Develop Novel, Cardiac Specific Capsids

CMRI has entered into a research collaboration with Zurich-based DiNAQOR, a genetic medicine platform company, to develop capsid gene therapy tools for treatment of both cardiovascular and kidney diseases.

CMRI Awarded Multiple Medical Research Future Fund Grants

Children’s Medical Research Institute (CMRI) was awarded multiple Medical Research Future Fund (MRFF) grants to help improve the lives of children living with genetic diseases. The MRFF, which is an initiative of the Australian Government, has funded research projects in cancer, gene therapy, and stem cell medicine at CMRI. Dr Anai Gonzalez-Cordero, head of theContinue reading “CMRI Awarded Multiple Medical Research Future Fund Grants”

Gene therapy trial success: game changer for children with SMA

New research has shown that gene therapy may provide an effective treatment for Spinal Muscular Atrophy (SMA), a devastating and fatal genetic condition. SMA affects the motor nerve cells in the spinal cord, causing progressive muscle weakness and preventing babies from being able to roll, sit up, crawl, walk and eventually breathe. Until recently, it was the leading genetic cause of infant death in Australia, occurring in 1 in every 10,000 births.

CMRI announces new collaboration with Gyroscope Therapeutics

Children’s Medical Research Institute and Gyroscope Therapeutics Holdings, a clinical-stage gene therapy company focused on treating diseases of the eye, today announced they have entered a research collaboration to develop next-generation clinical capsids, the protein shells of viral vectors used to deliver gene therapies. A team of researchers from CMRI and Gyroscope will work together in theContinue reading “CMRI announces new collaboration with Gyroscope Therapeutics”

Gene therapy project ranked top idea in Australia

A gene therapy project to save infants’ lives has been named the top ranked National Health and Medical Research Council (NHMRC) Ideas Grant for 2020, in what the lead researcher describes as ‘proof that we weren’t just dreamers and symbolic of the power of the genomic revolution’. Professor Ian Alexander and his team were awardedContinue reading “Gene therapy project ranked top idea in Australia”